Day 1 Venice, Italy

Venice is a city unlike any other. No matter how often you've seen it in photos and films, the real thing is more dreamlike than you could imagine. With canals where streets should be, water shimmers everywhere. The fabulous palaces and churches reflect centuries of history in what was a wealthy trading center between Europe and the Orient. Getting lost in the narrow alleyways is a quintessential part of exploring Venice, but at some point you'll almost surely end up in Piazza San Marco, where tourists and locals congregate for a coffee or an aperitif.

Day 2 Zadar, Croatia

Dalmatia's capital for more than 1,000 years, Zadar is all too often passed over by travelers on their way to Split or Dubrovnik. What they miss out on is a city of more than 73,000 that is remarkably lovely and lively despite—and, in some measure, because of—its tumultuous history. The Old Town, separated from the rest of the city on a peninsula some 4 km (2½ miles) long and just 1,640 feet wide, is bustling and beautiful: the marble pedestrian streets are replete with Roman ruins, medieval churches, palaces, museums, archives, and libraries. Parts of the new town are comparatively dreary, a testament to what a world war followed by decades of communism, not to mention a civil war, can do to the architecture of a city that is 3,000 years old. A settlement had already existed on the site of the present-day city for some 2,000 years when Rome finally conquered Zadar in the 1st century BC; the foundations of the forum can be seen today. Before the Romans came the Liburnians had made it a key center for trade with the Greeks and Romans for 800 years. In the 3rd century BC the Romans began to seriously pester the Liburnians, but required two centuries to bring the area under their control. During the Byzantine era, Zadar became the capital of Dalmatia, and this period saw the construction of its most famous church, the 9th-century St. Donat's Basilica. It remained the region's foremost city through the ensuing centuries. The city then experienced successive onslaughts and occupations—both long and short—by the Osogoths, the Croatian-Hungarian kings, the Venetians, the Turks, the Habsburgs, the French, the Habsburgs again, and finally the Italians before becoming part of Yugoslavia and, in 1991, the independent republic of Croatia. Zadar was for centuries an Italian-speaking city, and Italian is still spoken widely, especially by older people. Indeed, it was ceded to Italy in 1921 under the Treaty of Rapallo (and reverted to its Italian name of Zara). Its occupation by the Germans from 1943 led to intense bombing by the Allies during World War II, which left most of the city in ruins. Zadar became part of Tito's Yugoslavia in 1947, prompting many Italian residents to leave. Zadar's most recent ravages occurred during a three-month siege by Serb forces and months more of bombardment during the Croatian-Serbian war between 1991 and 1995. But you'd be hard-pressed to find outward signs of this today in what is a city to behold. There are helpful interpretive signs in English all around the Old Town, so you certainly won't feel lost when trying to make sense of the wide variety of architectural sites you might otherwise pass by with only a cursory look.

Day 3 Dubrovnik, Croatia

Nothing can prepare you for your first sight of Dubrovnik. Lying 216 km (135 miles) southeast of Split and commanding a jaw-dropping coastal location, it is one of the world's most beautiful fortified cities. Its massive stone ramparts and fortress towers curve around a tiny harbor, enclosing graduated ridges of sun-bleached orange-tiled roofs, copper domes, and elegant bell towers. Your imagination will run wild picturing what it looked like seven centuries ago when the walls were built, without any suburbs or highways around it, just this magnificent stone city rising out of the sea.In the 7th century AD, residents of the Roman city Epidaurum (now Cavtat) fled the Avars and Slavs of the north and founded a new settlement on a small rocky island, which they named Laus, and later Ragusa. On the mainland hillside opposite the island, the Slav settlement called Dubrovnik grew up. In the 12th century the narrow channel separating the two settlements was filled in (now the main street through the Old Town, called Stradun), and Ragusa and Dubrovnik became one. The city was surrounded by defensive walls during the 13th century, and these were reinforced with towers and bastions in the late 15th century.From 1358 to 1808 the city thrived as a powerful and remarkably sophisticated independent republic, reaching its golden age during the 16th century. In 1667 many of its splendid Gothic and Renaissance buildings were destroyed by an earthquake. The defensive walls survived the disaster, and the city was rebuilt in baroque style.Dubrovnik lost its independence to Napoléon in 1808, and in 1815 passed to Austria-Hungary. During the 20th century, as part of Yugoslavia, the city became a popular tourist destination, and in 1979 it was listed as a UNESCO World Heritage Site. During the war for independence, it came under heavy siege. Thanks to careful restoration, few traces of damage remain; however, there are maps inside the Pile and Ploce Gates illustrating the points around the city where damage was done. It's only when you experience Dubrovnik yourself that you can understand what a treasure the world nearly lost

Day 5 Civitavecchia, Italy

Italy's vibrant capital lives in the present, but no other city on earth evokes its past so powerfully. For over 2,500 years, emperors, popes, artists, and common citizens have left their mark here. Archaeological remains from ancient Rome, art-stuffed churches, and the treasures of Vatican City vie for your attention, but Rome is also a wonderful place to practice the Italian-perfected il dolce far niente, the sweet art of idleness. Your most memorable experiences may include sitting at a caffè in the Campo de' Fiori or strolling in a beguiling piazza.

Day 7 Barcelona, Spain

The infinite variety of street life, the nooks and crannies of the medieval Barri Gòtic, the ceramic tile and stained glass of Art Nouveau facades, the art and music, the throb of street life, the food (ah, the food!)—one way or another, Barcelona will find a way to get your full attention. The capital of Catalonia is a banquet for the senses, with its beguiling mix of ancient and modern architecture, tempting cafés and markets, and sun-drenched Mediterranean beaches. A stroll along La Rambla and through waterfront Barceloneta, as well as a tour of Gaudí's majestic Sagrada Famíliaand his other unique creations, are part of a visit to Spain's second-largest city. Modern art museums and chic shops call for attention, too. Barcelona's vibe stays lively well into the night, when you can linger over regional wine and cuisine at buzzing tapas bars.

Day 9 Casablanca, Morocco

The original settlement formed on the site of Casablanca by the Berbers became the kingdom of Anfa, and during the 15th century harboured pirates who raided the Portuguese coast. In retaliation for the attacks, the Portuguese destroyed Anfa and founded the town they called Casa Branca (white house). They remained here until an earthquake in 1755 and the town was subsequently rebuilt by Mohammed ben Abdallah, whose legacy of mosques and houses can still be seen in the old Medina. Casablanca acquired its present-day name when the Spanish obtained special port privileges in 1781. The French landed here in 1907, later establishing a protectorate and modelling the town on the port of Marseilles. Today Casablanca is Morocco's largest city, its most significant port and the centre of commerce and industry. The city is a vibrant fusion of European, African and Arabian influences and its French colonial architecture and art deco buildings seamlessly blend in with the busy, colourful markets. Please note that vendors in the souks can be very persistent and eager to make a sale.

Day 11 Santa Cruz de Tenerife, Spain

The largest of the Canary Islands, Tenerife is a beautiful and scenic island which enjoys year-round sunshine and is dominated by Mount Teide. The mountain range runs through the centre of the island, with fertile valleys on the northern side. In the central part of the range is the gigantic natural crater of the Cañadas del Teide, about 14 miles in diameter. Santa Cruz, the island's pretty capital, was originally a small fishing village but has now grown into a modern city, and also contains 16th-century civic buildings and ornate private mansions. Near the pier is the Santa Cruz Palmetum, a Botanical Garden covering an area of 29 acres, specialising in palms.

Day 18 Salvador de Bahia, Brazil

According to Salvador's adopted son Jorge Amado, "In Salvador, magic becomes part of the every-day." From the shimmering golden light of sunset over the Baía do Todos os Santos, to the rhythmic beats that race along the streets, Salvador, while no longer Brazil's capital, remains one of its most captivating cities. A large dose of its exoticism comes down to its African heritage—at least 70% of its 2,675,000 population is classified as Afro-Brazilian—and how it has blended into Brazil's different strands, from the native Indians to the Christian colonizers. Salvadorans may tell you that you can visit a different church every day of the year, which is almost true—the city has about 300. Churches whose interiors are covered with gold leaf were financed by the riches of the Portuguese colonial era, when slaves masked their traditional religious beliefs under a thin Catholic veneer. And partly thanks to modern-day acceptance of those beliefs, Salvador has become the fount of Candomblé, a religion based on personal dialogue with the orixás, a family of African deities closely linked to nature and the Catholic saints. The influence of Salvador's African heritage on Brazilian music has also turned the city into one of the musical capitals of Brazil, resulting in a myriad of venues to enjoy live music across the city, along with international acclaim for exponents like Gilberto Gil, Caetano Veloso, and Daniela Mercury. Salvador's economy today is focused on telecommunications and tourism. The still-prevalent African culture draws many tourists—this is the best place in Brazil to hear African music, learn or watch African dance, and see capoeira, a martial art developed by slaves. In the district of Pelourinho, many colorful 18th- and 19th-century houses remain, part of the reason why this is the center of the tourist trade. Salvador sprawls across a peninsula surrounded by the Baía de Todos os Santos on one side and the Atlantic Ocean on the other. The city has about 50 km (31 miles) of coastline. The original city, referred to as the Centro Histórica (Historical Center), is divided into the Cidade Alta (Upper City), also called Pelourinho, and Cidade Baixa (Lower City). The Cidade Baixa is a commercial area—known as Comércio—that runs along the port and is the site of Salvador's indoor market, Mercado Modelo. You can move between the upper and lower cities on foot, via the landmark Elevador Lacerda, behind the market, or on the Plano Inclinado, a funicular lift, which connects Rua Guindaste dos Padres on Comércio with the alley behind Cathedral Basílica. From the Cidade Histórica you can travel north along the bay to the hilltop Igreja de Nosso Senhor do Bonfim. You can also head south to the point, guarded by the Forte Santo Antônio da Barra, where the bay waters meet those of the Atlantic. This area on Salvador's southern tip is home to the trendy neighborhoods of Barra, Ondina, and Rio Vermelho, with many museums, theaters, shops, and restaurants. Beaches along the Atlantic coast and north of Forte Santo Antônio da Barra are among the city's cleanest. Many are illuminated at night and have bars and restaurants that stay open late.